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Surface Chemical Modification of Cellulose Nanocrystals and Its Application in Biomaterials
Authors:XiaoZhou M  YanJie Zhang  Jin Huang
Affiliation:1. School of Chemistry and Chemical Engineering, Joint International Research Laboratory of Bio-mass-Based Macromolecular Chemistry and Materials, Southwest University, Chongqing, 400715, China,2. School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, Hubei Province, 430070, China and 1. School of Chemistry and Chemical Engineering, Joint International Research Laboratory of Bio-mass-Based Macromolecular Chemistry and Materials, Southwest University, Chongqing, 400715, China;2. School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, Hubei Province, 430070, China
Abstract:Cellulose nanocrystals (CNCs) have been widely applied in biomaterials and show great biocompatibility and mechanical strength. In this review, the chemical reactions applied in CNC surface modification and their application in CNC based biomaterials are introduced. Furthermore, the conjugation of different functional molecules and nanostructures to the surface of CNCs are discussed, with focus on the binding modes, reaction conditions, and reaction mechanisms. With this introduction, we hope to provide a clear view of the strategies for surface modification of CNCs and their application in biomaterials, thus providing an overall picture of promising CNC-based biomaterials and their production.
Keywords:cellulose nanocrystals   chemical modification   immobilization   biomaterials   application
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