Heterocyclic synthesis with nitriles: Syntheses of some novel pyrazolo[1,5-a]pyrimidine and Pyrrolo[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine Derivatives |
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Authors: | F. M. Abdelrazek |
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Abstract: | 3,5-Diamino-4-phenacylpyrazoles 1a , b react with the cinnamonitriles 2a , b to afford the novel 7-phenacylpyrazolo[1,5-a]pyrimidine derivatives 4a – d , respectively. Compounds 4c , d undergo cyclization with trichloroacetonitrile to afford the novel tricyclic system pyrrolo-[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine derivatives 5e , f , respectively. |
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