| 青霉素直通法生产6-APA工业化研究 |
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| 引用本文： | 李士杰,魏光涛,张琳叶,贾荣荣.青霉素直通法生产6-APA工业化研究[J].精细与专用化学品,2014(3):29-30. |
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| 作者姓名： | 李士杰 魏光涛 张琳叶 贾荣荣 |
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| 作者单位： | 河北医药化工设计有限公司;广西大学化学化工学院;河北诚信有限责任公司; |
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| 摘 要： | 为了降低6-氨基青霉烷酸（6-APA）的生产成本,采用了直通、脱酯、萃取工艺对6-APA的生产工艺进行了改进,使得总收率和质量得到提高,大幅度降低了6-APA的生产成本,提高了6-APA及后续产品的市场竞争力.
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| 关 键 词： | 6-氨基青霉烷酸 直通工艺 脱酯 萃取 改进 |
Study on industrialization of penicillin direct process of 6-APA |
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| LI Shi-jie,WEI Guang-tao,ZHANG Lin-ye,JIA Rong-rong.Study on industrialization of penicillin direct process of 6-APA[J].Fine and Specialty Chemicals,2014(3):29-30. |
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| Authors: | LI Shi-jie WEI Guang-tao ZHANG Lin-ye JIA Rong-rong |
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| Affiliation: | 1. Hebei Pharmaceutical ＆Chemical Design Co. , Ltd. , Shijiazhuang 050000, China; 2. School of Chemistry and Chemical Engineering, Guangxi University,Nanning 530004,China; 3. H ebei Chengxin Co. , Ltd. , Shijiazhuang 051130,China) |
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| Abstract: | In order to reduce the production cost of 6-APA, the production process of 6-APA was improved by using the straight, degreasing, extraction process, the total yield and product＇s quality has been greatly improved, the production cost was reduced, follow up product market competitiveness was increased. |
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| Keywords: | 6-APA direct process degreasing extraction improvement |
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