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Pigments of Monascus
Authors:PJ BLANC  MO LORET  AL SANTERRE  A PAREILLEUX  D PROME  JC PROME  JP LAUSSAC  G GOMA
Affiliation:Authors Blanc, Loret, Santerre, Pareilleux, and Goma are with the Dept. Génie Biochimique et Alimentaire, UA-CNRS N°544, Institut National des Sciences Appliquées, Complexe Scientifique de Rangueil, F-31077 Toulouse Cedex, France.;Authors Prome and Prome are with the Laboratoire de Pharmacologie et de Toxicologie Fondamentales, CNRS, 205 route de Narbonne, F-31077 Toulouse Cedex, France.;Author Laussac is with the Laboratoire de Chimie de Coordination, CNRS, 205 route de Narbonne, F-31077 Toulouse Cedex, France.
Abstract:A chemically defined medium with glutamic acid as nitrogen source was devised for the culture of two species of Monascus (M. ruber and M. purpureus), resulting in optimum production of their pigments and their chemical structures (both free and complexed) were compared. Structural data on two major complex pigments in aqueous solution were obtained by IR, UV, NMR and MS. They were free pigments linked to glutamic acid by amino groups, where nitrogen replaced the pyronoid oxygen.
Keywords:Monascus  fungi  pigment  colorant  mass spectra
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