Lung phosphatidylcholine and fasting in male and female rats |
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Authors: | Masao Abe Makoto Endo Hiroshi Nagai |
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Affiliation: | (1) Department of Biochemistry, Sapporo Medical College, 060 Sapporo, Japan |
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Abstract: | Lung from male and female rats fasted for 4 days were used. Phospholipid, phosphatidylcholine and its molecular species were
analyzed in lungs from these rats and effects of fasting upon the biosynthesis of phosphatidylcholine in lungs from both sexes
were determined using radioactive choline. The molecular species of phosphatidylcholine in both male and female rats did not
differ with fasting except the monoenoic species. Incorporation of choline into phosphatidylcholine in both male and female
rats significantly increased after fasting, but distribution of radioactivity in phosphatidylcholine yielded similar values
in each group. These results suggest that the decrease of saturated phosphatidylcholine content after fasting may be not due
to specific change in saturated phosphatidylcholine. |
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