90Y电沉积的实验研究

研究了用电沉积方法从90Sr母液中分离医用90Y的工艺条件。以0.1 mol/L pH 2.5的(NH4)2SO4溶液为电沉积底液，以铂为阳极，铂或不锈钢为阴极，控制阴极电流密度0.5A/cm2，电沉积50min，90Y在阴极沉积率大于95%。阴极上的90Y用0.1~0.5mol/L的热硝酸洗脱后再次电沉积。二次电沉积后90Y/Sr90的分离系数大于8×105，洗脱收率大于70%。铂丝阴极上的90Y可用200~400μL 0.1~0.5mol/L的热硝酸洗脱，制成用于标记药物的90Y溶液；沉积有90Y的不锈钢阴极经热处理后，制成心血管放射性支架或医用敷帖片，其90Y的日浸出率分别小于1%和0.1%。残液中的90Sr经放置一段时间（20天）后，可用来再次分离90Y。

Milking Medical 90Y From 90Sr Solution by Electrodeposition

The technique of milking medical 90Y from 90Sr.cow by electrodeposition is studied. using 0.1 mol/L pH 2.5 (NH4)2SO4 as electrodeposition solution, platinum as anode ,and platinum or stainless steel as cathode, the current density of cathode is controlled at 0.5A/cm2 . After electrodeposition for 50 minutes ，more than 95% 90Y can be deposited quantitatively on the cathode. Though two-step electrodepositon, the 90Y/90Sr separation coefficient and elution recovery of 90Y are more than 8 ×105 and 70% respectively. The 90Y deposited on platinum cathode can be eluted by 200~400μL of 0.1~0.5mol/L hot HNO3, which is used to label monoclonal antibodies and peptide-receptor. The stainless steel cathode with deposited 90Y can be prepared to radioactive stent or medical patch, the former is used for the prevention of vascular restenosis, the later for the therapy of inflammation, the daily leaching efficiency of which are less than 1% and 0.1% respectively.90Sr remained in the deposition solution will generate new 90Y, so from which 90Y can be milked again