An Evaluation of Hydroxypropyl Starch as Disintegrant and Binder in Tablet Formulation |
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| Authors: | N. Visavarungroj J. P. Remon |
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| Affiliation: | a Laboratory of Pharmaceutical Technology State, University of Gent, Harelbekestraat, Gent, Belgium |
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| Abstract: | Hydroxypropyl and pregelatinized hydroxypropyl starch were evaluated as disintegrant and binder in tablet formulations. The study showed that the use of pure hydroxypropyl starch showed no advantage as a disintegrant or binder over the actually available tablet ingredients. Pregelatinized hydroxypropyl starch showed some good disintegrating properties and could be used as a binder in wet granulation. |
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