Symmetric 1,1'-Dimethylferrocene-Derived Amino Acids: Their Synthesis, Characterization, Ligational and Biological Properties With Cu(II), Co(II) and Ni(II) Ions

Some novel symmetric 1,1'-dimethylferrocene derived amino acids have been prepared by the reaction of 1,1'-ferrocenedimethyldichloride with amino acids (glycine, alanine, phenylalanine and tyrosine). Their Cu(II), Co(II) and Ni(II) complexes, of the type M(L)] where M = Cu(II) and L = L(1)-L(5)] and M(L)Cl(2)] where M-Co(II)and Ni(II), L = L(1)-L(5)] have been prepared. The dicarboxylic acids and their metal complexes were characterized by their physical, analytical and spectral data. The M(L)] complexes showed a square planar geometry whereas an octahedral geometry was observed for M(L)Cl(2)] complexes. The title dicarboxylic acids and their metal complexes have also been screened for their antibacterial activity.