| 聚乳酸类载紫杉醇纳米粒表面修饰的研究进展 |
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| 引用本文： | 裘迪,朱宏. 聚乳酸类载紫杉醇纳米粒表面修饰的研究进展[J]. 化工进展, 2009, 28(7): 1198 |
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| 作者姓名： | 裘迪 朱宏 |
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| 作者单位： | 南京工业大学材料科学与工程学院,江苏,南京,210009;南京工业大学材料科学与工程学院,江苏,南京,210009 |
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| 摘 要： | 聚乳酸/聚乳酸-羟基乙酸载紫杉醇纳米粒具有良好的缓释和靶向性能。本文总结目前最常用的制备方法，重点阐述载紫杉醇聚乳酸/聚乳酸-羟基乙酸纳米粒的表面修饰和特点。简要探讨了载紫杉醇聚乳酸/聚乳酸-羟基乙酸纳米粒未来的发展方向。
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| 关 键 词： | 紫杉醇 聚乳酸/聚乳酸-羟基乙酸 纳米粒 制备 表面修饰 |
Advances in research on surface modification of paclitaxel-polylactide nanoparticles |
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| QIU Di,ZHU Hong. Advances in research on surface modification of paclitaxel-polylactide nanoparticles[J]. Chemical Industry and Engineering Progress, 2009, 28(7): 1198 |
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| Authors: | QIU Di ZHU Hong |
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| Affiliation: | School of Material Science and Engineering，Nanjing University of Technology |
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| Abstract: | Paclitaxel-poly(lactic acid) (PLA)/poly(lactic-co-glycolic acid) (PLGA) nanoparticles have the capability of targeting,and controlled,sustained release of paclitaxel. This review summarizes the current preparation,with an emphasis on surface modification of paclitaxel-PLA/ PLGA nanoparticles, and their characteristics. Future development and further improvement of paclitaxel-PLA/ PLGA nanoparticles are also discussed. |
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| Keywords: | paclitaxel PLA/PLGA nanoparticles preparation surface modification |
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