| 萘基卟啉的合成与性能研究 |
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| 引用本文： | 陶敏莉,刘东志,周雪琴. 萘基卟啉的合成与性能研究[J]. 化学工程, 2005, 33(5): 72-74,78 |
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| 作者姓名： | 陶敏莉 刘东志 周雪琴 |
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| 作者单位： | 1. 天津大学,化工学院,天津,300072
2. 天津大学,材料学院,天津,300072 |
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| 摘 要： | 以萘基醛类化合物为原料与吡咯在丙酸中回流合成了3种含萘基的新型卟啉化合物,其中2种化合物尚未见文献报道,其结构通过1H NMR,IR和UV-V is确定。与四苯基卟啉相比,萘基的引入增大了卟啉环的共轭性,使得光学吸收波长与荧光发射波长均发生不同程度的红移,Q带吸收峰形改变且激发波长增长。结合卟啉光谱四轨道理论对该变化进行了讨论。
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| 关 键 词： | 卟啉 Q带 光动力疗法 红移 |
| 文章编号： | 1005-9954（2005）05-0072-03 |
Synthesis and characterization of novel naphthylporphyrins |
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| TAO Min-li,LIU Dong-zhi,ZHOU Xue-qin. Synthesis and characterization of novel naphthylporphyrins[J]. Chemical Engineering, 2005, 33(5): 72-74,78 |
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| Authors: | TAO Min-li LIU Dong-zhi ZHOU Xue-qin |
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| Affiliation: | 1. School of Chemical Engineering, Tianjin University, Tianjin 300072, China ;2. School of Materials Science and Engineering,Tianjin University,Tianjin 300072, China |
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| Abstract: | Three kinds of porphyrin with naphthyl group(tetranaphthylporphyrin,5-(4-hydroxyphenyl)-10,15,(20)-naphthylporphyrin and 5 -(4-hydroxynaphthy)-10,15,20-naphthyl-porphyrin) were synthesized and characterized by(~1H) NMR,IR and UV-Vis spectra.The introduction of naphthyl group can enhance the conjugate degree of the porphyrin,and cause red-shift of the absorption spectra.The results of fluorescence determination(exhibit) that the maximum excitation wavelength red-shifts by 3-5 nm in the naphthylporphyrins and the fluorescence intensity at 718 nm was enhanced by naphthyl.The experimental results show that naphthyl-porphyrins may be as a novel photosensitizer for photodynamic theraphy. |
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| Keywords: | porphyrin Q bands photodynamie theraphy red-shift |
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