Examining the volume efficiency of the cortical architecture in a multi-processor network model |
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Authors: | E Ruppin EL Schwartz Y Yeshurun |
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Affiliation: | ICRF Medical Oncology Unit, Western General Hospital, Edinburgh, U.K. |
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Abstract: | In two separate cohorts of breast cancer patients presenting without evidence of distant metastatic disease, high levels of tumour cyclic AMP binding proteins (> 8 pmol/mg cytosol protein) have been shown to be associated with poor prognosis in terms of both disease recurrence and overall survival. This association is independent of known established prognostic factors and allows the identification of a small subgroup of patients whose outlook warrants the implementation of aggressive systemic therapy. |
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