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正常人与胃癌患者尿液中6种微量元素的比较研究
引用本文:王立立,杨亮亮. 正常人与胃癌患者尿液中6种微量元素的比较研究[J]. 山东食品科技, 2012, 0(11): 424-426
作者姓名:王立立  杨亮亮
作者单位:[1]山东省医药工业研究所,山东济南250101 [2]山东省化学药物重点实验室,山东济南250101 [3]山东省高唐防疫站,山东高唐252800
摘    要:目的比较胃癌患者尿液中6种微量元素的差别。方法HNO3-HCl04(4:1,v/v)为消解体系,利用电感耦合等离子体发射光谱法测定正常人与胃癌患者尿液中锰、镍、铝、钻、铜、铬等6种微量元素的含量。结果胃癌患者尿液中锰、镍和钴降低显著,铜、铬升高显著,钼降低但无显著性差异。结论胃癌患者与正常人尿液中6种微量元素的水平有显著差别,起到预防、早期诊断及临床治疗胃癌的辅助作用,具有一定的临床意义。

关 键 词:微量元素  胃癌  尿液  电感耦合等离子体发射光谱法

Comparative Study on Six Trace Elements in Urine of Normal Human and Patients with Gastric Cancer
WANG Li - li,YANG Liang-liang. Comparative Study on Six Trace Elements in Urine of Normal Human and Patients with Gastric Cancer[J]. , 2012, 0(11): 424-426
Authors:WANG Li - li  YANG Liang-liang
Affiliation:1. Shandong Institute of Pharmaceutical Industry, Jinan 250101, China; 2. Shandong Provincial Key Laboratory of Chemical Drug Jinan 250101, China; 3. Shandong Gaotang Health and Quarantine Station, Gaotang 252800, China)
Abstract:Objective To compare the difference between normal human and patients with gastric cancer in six trace elements in urine. Methods The urine was dipped in HNO3-HClO4(4:1, v/v), six kinds of trace elements were determined in urine by inductively coupled plasma optical emission spectrometer. Results Compared with normal human, the contents of Mn, Ni and Mo in urine of patients with gastric cancer were significantly lower (P〈0.01) , Co was lower (0.01 〈P〈0.05) , Cu and Cr were significantly improved (0.01 〈P〈0.05 ) , and Mo was not significantly different. Conclusion The difference of six trace elements in urine is present between normal human and patients with gastric cancer, which provides a useful method for prevention, early diagnosis and clinical treatment of gastric cancer.
Keywords:trace elements  gastric cancer  urine  inductively coupled plasma optical emission spectrometer
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