非贵金属盐催化开环反应制备脂肪酸单甘酯的研究

月桂酸缩水甘油酯在非贵金属无机盐的催化作用下,经水解开环、冷却结晶纯化,可获得高纯度的月桂酸单甘酯产品。优化月桂酸单甘酯的合成反应条件,得出最佳条件为:反应溶剂乙腈,催化剂氯化铜,催化剂用量为月桂酸缩水甘油酯摩尔量的8%,反应时间24 h。将该合成及纯化方法应用于棕榈酸单甘酯和硬脂酸单甘酯的制备,并对纯化后的产品进行了傅里叶变换红外光谱和电喷雾电离质谱表征,结果表明该制备方法具有一定的普适性。

Preparation of fatty acid monoglyceride by non-precious metal salts catalyzed ring-opening reaction

High-purity glycerol monolaurate was obtained by hydrolytic ring-opening of glycidyl laurate and freezing crystallization, which catalyzed by non-precious metal inorganic salts. The preparation conditions of glycerol monolaurate were optimized as follows: with acetonitrile as solvent, and CuCl2 as catalyst, dosage of CuCl2 8%(based on the mole of glycerol monolaurate), reaction time 24 h. Furthermore, the method was applied to prepare glycerol monopalmitate and glycerol monostearate, and these products were characterized by FT-IR and ESI-MS, which confirmed the validity of the preparation method.