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| 鸡骨胶原蛋白肽对D-半乳糖致衰小鼠抗氧化性的研究 | |
| 引用本文： | 张根生,符群,岳晓霞.鸡骨胶原蛋白肽对D-半乳糖致衰小鼠抗氧化性的研究[J].食品工业科技,2010(1). |
| 作者姓名： | 张根生 符群 岳晓霞 |
| 作者单位： | 1. 东北林业大学林学院,黑龙江哈尔滨,150040;哈尔滨商业大学食品工程学院,黑龙江哈尔滨,150076 2. 东北林业大学林学院,黑龙江哈尔滨,150040 3. 哈尔滨商业大学食品工程学院,黑龙江哈尔滨,150076 |
| 基金项目： | 黑龙江省农业科技攻关项目(GB06B403-2) |
| 摘 要： | 目的:采用D-半乳糖注射昆明种成年小鼠,建立衰老模型,研究鸡骨胶原蛋白肽对D-半乳糖致衰小鼠抗氧化能力的影响。方法:昆明种成年小鼠,随机分为正常组、模型组、低剂量组、高剂量组及VE对照组。以小鼠血清、肝脏及脑组织中的SOD、GSH-Px、CAT的活性及MDA含量为指标,考察鸡骨胶原蛋白肽在体内的抗氧化性能。结果:鸡骨胶原蛋白肽能够显著提高致衰小鼠体内肝组织、脑组织中的GSH-Px、CAT(P<0.05)和SOD活力(P<0.05),而血清、肝组织和脑组织中的MDA含量(P<0.05)则显著降低。结论:摄入适当的鸡骨胶原蛋白肽可以有效地增强小鼠机体的抗氧化能力,从而延缓D-半乳糖诱发的小鼠衰老。 |
| 关 键 词： | 胶原蛋白肽 鸡骨 抗氧化性 |
Study on antioxidation of D-galactose induced aged rat by hydrolyzed collagen from chicken bone |
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| ZHANG Gen-sheng,FU Qun,YUE Xiao-xia.Study on antioxidation of D-galactose induced aged rat by hydrolyzed collagen from chicken bone[J].Science and Technology of Food Industry,2010(1). | |
| Authors: | ZHANG Gen-sheng FU Qun YUE Xiao-xia |
| Affiliation: | ZHANG Gen-sheng1,2,FU Qun1,YUE Xiao-xia2(1.Food Science Department,Northeast Forestry University,Harbin 150040,China,2.College of Food Engineering,Harbin Commerce University,Harbin 150076,China) |
| Abstract: | Objective:Kunming mouse were given D-galactose for developing the aging model to investigate the influence of hydrolyzed collagen on the antioxidation of D-galactose induced aging rat.Methods:The mouse were randomly divided into five groups involved in group without treatment,model group,low-dose hydrolyzed collagen,high-dose hydrolyzed collagen and group treated with VE,the activity of SOD,MAT,and GSH-Px in serum,liver as well as the contents of MDA were determined.Results:Hydrolyzed collagen from chicken ... |
| Keywords: | hydrolyzed collagen chicken bone antioxidation |
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