Fructosamine in blood serum, binding and degradation of 125J-insulin by erythrocyte receptors in young persons with type I diabetes--effect of physical exercise

The aim of investigation was the determination of the effect of regular physical exercise of intensity 35% VO2max on glycolysation of proteins, expressed by fructosamine concentration in blood serum and on insulin sensitivity of erythrocyte receptors in children with diabetes mellitus type I. The investigations were performed with 10 young persons with diabetes mellitus type I, during their sanatorium treatment. During 21 days the children effected every day a 20-minutes ergometric exercise of intensity equivalent approximately to 35% VO2max. Before the 3-weeks therapy and after its termination the examined children have performed an ergometric test exercise, with collection of blood samples. Obtained results allow to ascertain, that regular aerobic exercise contributed to the growth of physical efficiency expressed by the VO2max value, reduction in fructosamine level in blood serum, increase in insulin sensitivity of erythrocyte receptor and improved effort tolerance related to glycemia.