蛋清高F值寡肽对受试小鼠皮肤中羟脯氨酸含量影响的研究

蛋清高F值寡肽就是一种由2～5个氨基酸残基所组成的混合小肽体系,已知具有辅助治疗肝性脑病,抗疲劳、耐缺氧、降血脂等生理功能。本实验主要针对蛋清高F值寡肽是否对小鼠皮肤中羟脯氨酸含量存在影响进行实验研究,综合分析了不同浓度蛋清高F值寡肽液对小鼠灌胃30d和90d的小鼠皮肤中羟脯氨酸含量的变化。研究发现:不同浓度蛋清高F值寡肽均可以明显提高受试小鼠皮肤中羟脯氨酸含量,其中浓度为10%的蛋清高F值寡肽液无论是对灌胃30d还是灌胃90d的小鼠皮肤中羟脯氨酸含量影响都是极显著。

Effects of High F Ratio Oligopeptide from Egg White on L-hydroxyproline Content in Skin of Mice

High F value oligoeptide is a kind of small peptide mixture which contains 2 to 5 amino acid residues.It has the functions of anti-fatigue,anti-anoxic and other physiological function,and it also could be used in treament of hepatic encephalopathy as an auxiliary treatment.The effect of the high F value oligopeptide from egg white on the L-hydroxyproline content in skin of mice was investigated in this study,and a comprehensive analysis on the effects of high F value oligopeptide at different concentrations was carried out.The results showed that the high F value oligopeptide can significantly impove the content of L-hydroxyproline in skin of mice,especially when the concentration of high F value oligo-peptide is 10% no matter intragastric administration for 30 d or 90 d.