Effect of Chondroitin Sulfate on the Crystal Growth of Hydroxyapatite |
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| Authors: | Sang-Hoon Rhee Junzo Tanaka |
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| Affiliation: | Korea Research Institute of Chemical Technology, Taejon 305–600, Korea;National Institute for Research in Inorganic Materials, Tsukuba, Ibaraki 305–0044, Japan |
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| Abstract: | The effect of chondroitin sulfate (ChS) templates on the crystal growth of hydroxyapatite (HAp) was investigated. HAp particles and 60HAp/40ChS hybrid (in wt%) were synthesized by using a precipitation method with a calcium hydroxide suspension and phosphoric acid solutions without and with ChS, respectively. The sizes of HAp crystals formed without ChS templates were around 75 nm × 10 nm while those with ChS templates were around 12 nm × 6 nm. The inhibitory effect of ChS templates on the crystal growth of HAp is explained in terms of organic matrix regulated HAp formation following steric hindrance by adjacent crystals. |
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| Keywords: | hydroxyapatite crystals |
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