Enhancement of the Antitumour Activity for the Synthesised Dodecylcysteine Surfactant using Gold Nanoparticles |
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| Authors: | E. M. S. Azzam S. M. I. Morsy |
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| Affiliation: | (1) Applied Surfactant Laboratory, Petrochemicals Department, Egyptian Petroleum Research Institute, Nasr City, 11727 Cairo, Egypt |
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| Abstract: | In this paper, the surfactant dodecylcysteine hydrochloride was synthesised. The surface parameters of the synthesised surfactant were studied using a surface tension technique. The surface parameters show a good surface activity of the prepared surfactant in aqueous solution. The self-assembling behaviour of the synthesised surfactant comparing with that of cysteine compound on the prepared gold nanoparticles was confirmed using transmission electron microscope (TEM) measurements. The effect of self-assembling of this surfactant on the size of gold nanoparticles was studied using TEM images. The antitumour activity of the prepared surfactant without and with the gold nanoparticles was investigated. The results show that the antitumour activity of the prepared surfactant was enhanced with the presences of the gold nanoparticles. |
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| Keywords: | Dodecylcysteine hydrochloride surfactant Gold nanoparticles Surface properties Antitumour activity |
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