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Emerging Perspectives in the Synthesis of Novel Degradable Biomedical Copolymers
Authors:Xiongyan Zhao  Mingzhu Wang  Weina Gao  Zhanying Sun  Jiang Xie
Affiliation:1. State Key Laboratory Breeding Base, Hebei Key Province Laboratory of Molecular Chemistry for Drug, Shijiazhuang, People's Republic of China;2. College of Material Science and Engineering, Hebei University of Science and Technology, Shijiazhuang, People's Republic of China;3. College of Material Science and Engineering, Hebei University of Science and Technology, Shijiazhuang, People's Republic of China;4. Institute of Chemistry, Chinese Academy of Sciences (ICCAS), Beijing, People's Republic of China
Abstract:Biodegradable polymer is playing an increasingly significant role in the development of biomedical materials due to its good biocompatibility and biodegradability, and is undoubtedly the focus in the biomedical fields, such as controlled drug delivery, tissue engineering, and regenerative medicine. In this review, some new degradable biomedical copolymers reported over the past 5 years are introduced and discussed in combination with some our research results. The molecular design, chemical structures and related properties of these novel biodegradable copolymers are reported. In summarizing the review, the development, potential applications and future directions of the degradable biomedical copolymers are discussed.
Keywords:Biodegradable polymers  Biomaterials  Poly(amino acid)  Polyanhydride  Polyester copolymer
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