“背包式”反应精馏集成过程研究进展

“背包式”反应精馏是一种反应器与精馏塔既相互独立又相互耦合的离散集成技术。由于反应与分离处于不同空间位置，能够突破传统反应精馏对工况的限制，拓宽应用范围，且便于工程放大。本文综述了国内外“背包式”反应精馏从基础到应用的研究概况。从转化率、选择性、塔内温度、组成分布等方面，分析了“背包式”反应精馏与传统反应精馏的等效性，指出“背包式”反应精馏的优势在于工况的灵活选择利于实现反应与分离能力的最佳匹配。介绍了“背包式”反应精馏在稳态模拟与优化、动态模拟及控制等方面的研究进展，并从不同工况反应与精馏集成技术的应用、便捷的催化剂装填与反应器设计应用两个角度归纳了该技术的应用进展。最后，从优化设计理论、先进控制方法、能量综合利用以及强化酶催化反应等方面对“背包式”反应精馏进一步的研究与应用进行展望。

Review on investigation of side-reactor column configuration technology

Side-reactor column (SRC) configuration is a discrete integration technology in which the reactors and distillation column are not only independent but also coupled with each other. The limitation of operation conditions in traditional reactive distillation (RD) could be overcame due to the different location of reaction and separation, expanding the RD application areas and facilitates industrial amplification. This study reviewed the SRC technology from basic to application. The equivalence of SRC and RD were analyzed from the aspects of conversion, selectivity, temperature, and composition profile. The advantage of SRC was the flexible adjustment of operating conditions, which could realize the perfect match between reaction and separation capacity. The developments in steady state simulation and optimization, dynamic simulation and control strategies of SRC were introduced. It also summarized the current applications of this technology from two aspects: integrated technology of reaction and distillation under different working conditions, convenient catalyst loading and reactor design. The future research and application of SRC were prospected from the aspects of optimization design theory, advanced control methods, comprehensive utilization of energy, enhanced enzyme-catalyzed reaction.