| 应用鸡卵细胞大量制备多克隆抗体 |
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| 引用本文： | 尹红章,李秀华.应用鸡卵细胞大量制备多克隆抗体[J].粉末涂料与涂装,1993,6(4):167-169. |
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| 作者姓名： | 尹红章 李秀华 |
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| 作者单位： | 中国药品生物制品检定所，中国药品生物制品检定所，中国药品生物制品检定所，中国药品生物制品检定所，中国药品生物制品检定所，中国药品生物制品检定所 北京 100050，北京 100050，北京 100050，北京 100050，北京 100050，北京 100050 |
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| 摘 要： | 用三种不同来源的抗原(基因工程HBVe、HCV核心区抗原和GM—CSF)免疫鸡,观察血清及卵黄中特异性抗体的应答,结果经免疫的鸡对这3种抗原均有免疫应答,所产卵的卵黄中可测出大量的有活性的抗体。提示鸡源性抗体在生物制品开发应用方面有一定的前景。
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| 关 键 词： | 多克隆抗体 卵黄抗体 免疫应答 |
Mass Preparation of Polyclonal Antibody with Hen Egg cells |
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| Yin Hongzhang et al National Institute for the Control of Pharmaceutical and Biological Products,Beijing.Mass Preparation of Polyclonal Antibody with Hen Egg cells[J].Chinese Journal of Biologicals,1993,6(4):167-169. |
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| Authors: | Yin Hongzhang National Institute for the Control of Pharmaceutical and Biological Products Beijing |
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| Abstract: | Specific antibody responses in the serum and yolk of hens immunized with recombinant HBeAg, HCV core antigen and human GM-CSF antigen were observed. The result showed that all the three antigens could induce specific antibodies in immunized hens, and significamt quantity of active an- tibodies could be detected in yolk of eggs laid by the hens. It indicated that antibodies derived from hens opened up prospects for development and application of biologieals. |
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| Keywords: | Polyclonal antibody Yolk antibody Immune response |
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