| 5-氯-2-[2-羟基-3-叔丁基-5-(3-丙酸甲酯基)苯基]-2H-苯并三唑的合成 |
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| 引用本文： | 胡海威,温辉梁,赵燕. 5-氯-2-[2-羟基-3-叔丁基-5-(3-丙酸甲酯基)苯基]-2H-苯并三唑的合成[J]. 精细石油化工, 2006, 23(2): 31-34 |
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| 作者姓名： | 胡海威 温辉梁 赵燕 |
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| 作者单位： | 南昌大学理学院化学系,江西,南昌,330047;南昌大学食品科学教育部重点实验室,江西,南昌,330047 |
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| 摘 要： | 通过重氮偶合、还原环化和酯化反应合成了5-氯2-[2-羟基-3-叔丁基-5-(3-丙酸甲酯基)苯基]-2H-苯并三唑,并进行了工业放大实验,收率53．0%～55．0%。偶合反应时,以十二烷基苯磺酸钠为乳化试剂,pH=5～8,收率为73．7%；采用n(偶合物)：n(保险粉)：n(NaOH)=1．0：3．5：15．8进行还原反应,收率81．0%。用MS和~1H NMR谱图表征了产物的结构,测定了产物的紫外吸收和透光率。
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| 关 键 词： | 苯并三唑 紫外线吸收剂 重氮偶合 还原 酯化 |
| 收稿时间： | 2005-06-13 |
| 修稿时间： | 2005-12-02 |
SYNTHESIS OF 5-CHLORO-2-[2-HYDROXY-3-tert-BUTYL-5-(3-METHOXYCARBONYLETHYL)-PHENYL]-2H-BENZOTRIAZOLE |
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| Hu Haiwei,Wen Huiliang,Zhao Yan. SYNTHESIS OF 5-CHLORO-2-[2-HYDROXY-3-tert-BUTYL-5-(3-METHOXYCARBONYLETHYL)-PHENYL]-2H-BENZOTRIAZOLE[J]. Speciality Petrochemicals, 2006, 23(2): 31-34 |
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| Authors: | Hu Haiwei Wen Huiliang Zhao Yan |
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| Affiliation: | 1. Department of Nanchang University, Nanchang 330047, Jiangxi, China; 2. The Key Lab of Food Science of MOE , Nanchang University, Nanchang 330047, Jiangxi , China |
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| Abstract: | 5-Chloro-2-[2-hydroxy-3-tert-butyl-5-(2-methoxycarbonylethyl)-phenyl]-2H-benzotriazole was synthesized through four steps including diazotization,coupling,hydrogenation and esterifica- tion.The yield in laboratory and the scaled up process was 56.2% and 53.0%-55.0%,respectively. In the process of coupling,at pH=5-8 with sodium dodecyl benzenesulfonate as emulsification,the yield was 73.7%.In the process of hydrogenation,with the optimal ratio of n(dye):n(rongalite):n (sodium hydroxide)=1.0:3.5:15.8,the yield was 81.0%.The product was characterized by MS and ~1H NMR.The abilities of UV-absorption and permeating light of the product were measured. |
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| Keywords: | benzotriazole ultraviolet light absorber diazotization-coupling hydrogenation esterification |
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