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Apoptosis: getting rid of the bodies
Authors:VA Fadok  PM Henson
Affiliation:Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA.
Abstract:Cells that die by apoptosis need to be removed before lysis to preserve tissue integrity and function. Recent studies have identified components of the uptake machinery used by phagocytes, but much remains to be learnt, particularly about the recognition mechanisms and their coupling to the uptake machinery.
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