多壁碳纳米管对鲤鱼各组织SOD酶活性的影响

应用浸浴法研究多壁碳纳米管（MWCNTs）对鲤鱼（cyprinl Jscarpioio）腮、肝、肾和脑中超氧化物歧化酶（SOD）的影响，结果显示：低浓度（0．1，lmg·L^-1）处理组暴露后3d，腮和肝中的SOD活性显著高于对照组（p〈0．01），肾和脑中SOD活性与对照组无显著差异（p〉0．05）。随着暴露时间延长，各组活性降低，至9d，肝和肾中SOD活性显著低于对照组（p〈0．05），腮和脑中SOD活性与对照组无显著差异（p〉0．05）。高浓度（10mg·L^-1）处理组，整个暴露期间，肝中SOD的活性显著低于对照组（p〈0．01），脑中SOD的活性与对照组无显著差异（p〉0．05），腮和肾中SOD活性在暴露后3d，与对照组无显著差异（p〉0．05），暴露后6d、9d，活性显著低于对照组（p〈0．05）。提示：MWCNTs对鲤鱼各组织中SOD酶活性的影响有时间和浓度依赖性。

Effect of Multi-wall Carbon Nanotubes on Superoxide Dismutase Activity in Tissues of Cyprinus Carpioio

The effect of multi-wall carbon nanotubes （MWCNTs） on superoxide dismutase activity （SOD） in liver, brain, kidney, and gill tissues of cyprinus carpio were studied with addictive indexmethod. The results showed that the activities of SOD in liver and gill , at the concentration of 0.1,1 mg·L^-1 group, were Significantly higher than those in the control group （p〈0.01）after cyprinus carpio were exposed 3 days. Nevertheless, the activities of SOD were no notably difference between the kindey , brain tissues and the control group （p〉0.05）. The activities of SOD were reduced in all treatment groups along the extended exposure time. When the cyprinus carpio were exposed 9days, the activities of SOD in liver and kidney were significantly lower than those in the control group （P〈0.05）. But the activities of SOD were were no significantly difference between the gill, brain and control group. At the concentration of 10mg·L^-1group, the activities of SOD in liver were significantly lower than those in the control group （p〈0.01）during the whole experiment. However, no significant changes were observed in the activities of SOD in brain （p〉0.05）. Although the activities of SOD in gill and kidey, at the concentration of 10mg·L^-1 group, were no significantly change when copared to the control group （p〉0.05） after cyprinus carpio were exposed 3 days, the activities of SOD were significantly lower than those in the control group （P〈0.05） after cyprinus carpio were exposed 6,9days.It indicated that the MWCNTs exhibited time and concentrationdependent.