分子印迹技术在水产品质量安全检测中的应用研究进展

分子印迹技术是以目标分子为模板,合成对目标分子有专一性识别性能的高分子聚合物的技术。由于分子印迹聚合物具有构效预定性、特异识别性的优点,能够解决传统样品前处理和分析测定中存在的非特异性吸附问题,广泛应用于生物样品中药物的分离、提纯和分析。本文综述了分子印迹技术的原理以及在水产品质量安全检测方面的应用进展,主要包括分子印迹技术在水产品样品前处理和分析测定过程中的应用。与传统的样品前处理技术相比,将分子印迹技术与样品前处理技术相结合,具有更好的选择性、重复性和实用性,提高了灵敏度。本文对分子印迹技术存在的不足以及在水产品质量安全检测中应用领域的发展方向作出展望。

Research progress on application of molecular imprinting technique in detection of quality and safety of aquatic products

Molecular imprinting technique is a process for preparing functional polymers which are capable of specifically recognizing targeted molecules with target molecules as templates. Because of the advantages of structural predetermination and specific recognition, molecularly imprinted polymers are widely used in the separation, purification and analysis of drugs in biological samples to eliminate the non-specific adsorption in the traditional sample preparation and determination. In this paper, the principle of molecular imprinting technique was introduced, and the latest progress of application in detection of quality and safety of aquatic products was described, mainly including its application in the pre-treatment and analysis of aquatic products. Compared with the traditional sample pretreatment technology, the pretreatment technology combined with molecular imprinting technique had better selectivity, repeatability, practicability and sensitivity. Finally, the shortcomings and future of application of molecular imprinting technology in detection of quality and safety of aquatic products were also discussed.