Synthesis and Characterization of Core-shell Hydroxyapatite/chitosan Biocomposite Nanospheres |
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| Authors: | LI Xiangnan CHEN Xiaoming LI Shipu PENG Zhiming |
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| Affiliation: | LI Xiangnan1,2,CHEN Xiaoming1,LI Shipu1,PENG Zhiming1 (1. Biomedical Materials , Engineering Research Center,Wuhan University of Technology,Wuhan 430070,China,2. School of Chemical Engineering,China) |
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| Abstract: | Novel core-shell hydroxyapatite/chitosan biocomposite nanospheres were synthesized in a multiple emulsion. The multiple emulsion was a w/o/w emulsion, made of diammonium phosphate solution as an inner aqueous phase, cyclohexane as an oil phase, and calcium nitrate solution and chitosan solution as an outer aqueous. The forming mechanism of core-shell spheres and the influence of temperature on the morphology of the nanospheres were investigated. The diameter of the resulting core-shell nanospheres was 100-2... |
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| Keywords: | multiple emulsion core-shell nanosphere chitosan hydroxyapatite |
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