Symposium review: The role of adipose tissue in transition dairy cows: Current knowledge and future opportunities

Adipose tissue (AT) is a central reservoir of energy stored in the form of lipids. In addition, AT has been recognized as an immunologically and endocrinologically active tissue of dairy cattle. The recent literature on AT biology of transition dairy cows has often focused on the possible negative effects that originate from excessive body fat. However, the highly efficient energy-storage capability of this tissue is also vital to the adaptability of dairy cattle to the change in nutrient availability, and to support lactation and reproduction. An excessive degree of mobilization of this tissue, however, is associated with high circulating fatty acid concentrations, and this may have direct and indirect negative effects on reproductive health, productivity, and disease risk. Furthermore, rapid lipolysis may be associated with postpartum inflammation. Research on the role of AT is complicated by the greater difficulty of accessing and measuring visceral AT compared with subcutaneous AT. The objective of this review is to provide a transition cow–centric summary of AT biology with a focus on reviewing methods of measuring AT mass as well as to describe the importance for production, health, and reproductive success.