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Mechanistic modeling of hydrophobic interaction chromatography for monoclonal antibody purification: process optimization in the quality by design paradigm |
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| Authors: | Lalita Kanwar Shekhawat Monu Chandak Anurag S Rathore |
| Affiliation: | Department of Chemical Engineering, Indian Institute of Technology, New Delhi, India |
| Abstract: | |
| Keywords: | hydrophobic interaction chromatography mechanistic modeling general rate model exponentially modified Langmuir adsorption model monoclonal antibody aggregate removal |