生物玻璃的研究与发展

生物玻璃的研究已达二十多年，现已成为材料学、生物化学以及分子生物学的交叉学科。由于生物玻璃具有人体硬或软生命组织有机联结的特点，在骨科、牙科、中耳等方面，对人体的伤害部位可进行修护治疗以至康健，其前景可观。生物玻璃主要由Ｓｉ、Ｎａ、Ｃａ以及Ｐ的氧化物组成。被发现具有生物活性的玻璃已有一系列组成，并且对这些系列玻璃已积累了大量的模拟人体溶液实验数据。常用的模拟人体溶液有两种：其一是Ｔｒｉｓ缓冲液；其

Bioactive Glasses: Research and Applications

Bioactive glasses have been studied over two decaaes using the sciences of materials, biology and biochemistry. The bioactive glasses form chemical bonds directly with living tissues(either hard or soft tissues) and their applications are promising in the repair and recoustruction of diseased or damaged Parts of human skeleton such as in prcotheses for dentistry and surgery etc. The bioactive glasses consist of silica,and sodium, calcium and phosphate oaldes in very specific ranges. The highly bioative glasses are used in the form of bulk implants, coatings and powders. A large amount of In-Vitro ted data for the bioative glasses have been collected using two major physiological solutions: tris(hydronymethyl aminomethane)baer and simulated body fluid (SBF). Theoretical studies in In-Vitro environments show that five surface reaction stages and the negstive zeta potential developed on the bioactive glasses surface induce the Precipitation and crystallization Of hydroxyapatite (HA) which is associated with the bonding to tissues.The actually bonding has been found in a number of In-Vivo tests. Because of these achievements, some of the bioactive glass products have alredy appeared in market, including implants to redore hearing,to replace teeth and powder to prevent tooth loss from gum disease. A good understanding of how the inorgedc materials bond with the living organics will bring a race revolution in worldwide use of these biomaterials to improve the quality of life.