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HfO2:Eu nanoparticles excited by X-rays and UV-visible radiation used in biological imaging
Authors:Jarosław Kaszewski  Jarosław Olszewski  Julita Rosowska  Bartłomiej Witkowski  Łukasz Wachnicki  Karolina Wenelska  Ewa Mijowska  Zdzisław Gajewski  Marek Godlewski  Michał M. Godlewski
Affiliation:1. Institute of Physics, Polish Academy of Sciences, Al. Lotników 32/46, 02-668 Warsaw, Poland;2. Veterinary Research Centre, Department of Large Animal Diseases with Clinic, Faculty of Veterinary Medicine, Warsaw University of Life Sciences – SGGW, Nowoursynowska 100, 02-797 Warsaw, Poland;3. Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences – SGGW, Nowoursynowska 159, 02-776 Warsaw, Poland;4. Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, al. Piastów 45, 70-311 Szczecin, Poland
Abstract:Europium doped hafnium dioxide nanoparticles were crystallized using biologically friendly microwave hydrothermal method and employed in observation of small rodents tissues. Main solvent in synthesis is water, in consequence nanoparticles are found surrounded by thin hydroxide layer. Size of the nanoparticles is controlled by temperature of calcination. 1200 °C heating causes drop of luminescence intensity, explained as damage of high symmetry surface emission centers in the nanocrystals. On the other hand, growth of crystallites increases intensity of X-ray and electron beam excited luminescence. This makes them promising activator in photodynamic therapy.
Keywords:Corresponding author. Fax: (+48) 22 116 35 07.  Europium  Scintillators  Hydrothermal  Nanoparticles  Rare earths
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