Association between Microbiota and Nasal Mucosal Diseases in terms of Immunity |
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| Authors: | Junhu Tai Mun Soo Han Jiwon Kwak Tae Hoon Kim |
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| Affiliation: | Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Korea University, Seoul 02841, Korea; (J.T.); (M.S.H.); (J.K.) |
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| Abstract: | The pathogenesis of nasal inflammatory diseases is related to various factors such as anatomical structure, heredity, and environment. The nasal microbiota play a key role in coordinating immune system functions. Dysfunction of the microbiota has a significant impact on the occurrence and development of nasal inflammation. This review will introduce the positive and negative roles of microbiota involved in immunity surrounding nasal mucosal diseases such as chronic sinusitis and allergic rhinitis. In addition, we will also introduce recent developments in DNA sequencing, metabolomics, and proteomics combined with computation-based bioinformatics. |
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| Keywords: | microbiota nasal mucosa immunity chronic rhinosinusitis allergic rhinitis |
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