纯天然酵母提取物的皮肤美白功效

通过离体实验和人体实验分别验证了新近开发的皮肤美白原料纯天然酵母提取物Natriance B rightener(NB)的美白功效。离体组织切片实验结果表明,与安慰剂相比,质量分数为0.5%和1.0%的NB水溶液对黑色素的抑制率分别为55.8%(p<0.05)和81.2%(p<0.01),而质量分数为1.0%的曲酸水溶液(阳性对照)对黑色素的抑制率为25.9%(p<0.05)。在双盲人体实验中,相比使用安慰剂一侧的皮肤,使用质量分数为3%NB美白霜的皮肤亮度(L*值)和皮肤个体类型角(ITA°)在整个测试期间呈增长趋势,截至测试42 d时,仍然保持30%以上的增长(p<0.05);皮肤的黑色素指数(M I)值在整个测试期间呈下降趋势,截至42 d时,仍然保持38%的下降(p<0.05)。可见NB有显著高于对照组的美白功效(p<0.05)。

Whitening efficacy study for yeast extract

Natriance Brightener(NB) is a new skin whitening active ingredient used in cosmetic products extracted from yeast(saccharamyces).Both in vitro and in vivo tests were used to demonstrate its skin whitening efficacy.Results of in vitro test showed that,as compared with that of the placebo,the inhibition rate of formation of melanin of aqueous solution of NB with mass fraction of 0.5% and 1.0% achieves 55.8%(p<0.05) and 81.2%(p<0.01) respectively,while that of aqueous solution of Kojic acid(positive control) with mass fraction of 1% achieves 25.9%(p<0.05).Results from double-blinded in vivo test showed that,as compared with the placebo side,the sample containing 3%(mass fraction) NB showed positive efficacy on skin luminance(L* value) individual topology angle(ITA°) and melanin index(MI).Skin luminance and ITA° keep statistically significantly increasing for more than 30% throughout the test period of 42 d(p<0.05).Melanin index keep significantly decreasing for 38% during the whole test period of 42 d(p<0.05).