Neuropsychologic effects of carotid endarterectomy |
| |
Authors: | R Antonelli Incalzi A Gemma F Landi F Pagano O Capparella F Snider R Manni P Carbonin |
| |
Affiliation: | Istituto di Medicina Interna e Geriatria, Roma, Italy. |
| |
Abstract: | This study assessed neuropsychologic changes after internal carotid endarterectomy using a design that limited the confounding effects of surgical and anesthesiological stress. Twenty-eight patients (mean age = 65.9 years, SD = 8.4, range 45-79), underwent extensive neuropsychological assessment before and on the seventh day after carotid endarterectomy for symptomatic carotid stenosis greater than 75%. A similarly assessed control group of 30 patients underwent elective orthopaedic surgery. A third cognitive assessment was performed 4 months postoperatively on a subgroup of the study patients. No significant cognitive change occurred in the control group. The study patients showed significant improvement in verbal memory, constructive abilities, verbal attainment, and visual attention; a trend towards further improvement of verbal functions was evident at the late postoperative assessment. No side-specific cognitive change was observed. In conclusion, carotid endarterectomy performed for currently accepted indications significantly improves several cognitive functions. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|