苦荞调控糖脂代谢作用及其生物学机制研究进展

目前，苦荞因具有调节糖脂代谢的功效已日渐成为研究热点，其主要化学成分包括多种氨基酸、脂肪酸、维生素以及黄酮类物质。以苦荞饮食替代日常饮食，有助于降低血糖、血脂水平，改善胰岛素抵抗等。苦荞中的苦荞黄酮、苦荞蛋白等成分被认为与改善糖脂代谢相关，其主要通过抑制α-葡萄糖苷酶活性、增加胰岛素敏感性等作用机制达到改善糖代谢的作用，并通过吸附胆酸盐、调控血脂代谢通路等机制达到改善脂代谢的作用。本文综述了苦荞调节糖脂代谢的物质基础及作用机制研究，并对未来苦荞的研究方向和应用前景进行了分析，以期促进苦荞的深入研究和应用，为肥胖、高血脂、2型糖尿病等慢性疾病的预防和早期治疗提供新思路。

Recent Advances in Understanding the Role and Mechanism of Action of Tartary Buckwheat in Regulating Glucolipid Metabolism

Currently, tartary buckwheat is increasingly becoming a research hotspot due to its role in regulating glucolipid metabolism. The major chemical composition of tartary buckwheat includes multiple amino acids, fatty acids, vitamins, and flavonoids. Tartary buckwheat can be used as an alternative to reduce blood glucose and lipid levels and to improve insulin resistance. Flavonoids and proteins in tartary buckwheat have been recognized to be related to the improvement of glucolipid metabolism, which can improve glucose metabolism via inhibiting α-glucosidase activity and enhancing insulin sensitivity and improve lipid metabolism via bile salt absorption and regulating lipid metabolism pathways. This paper summarizes the material basis and mechanism for the regulation of tartary buckwheat on glucolipid metabolism and discusses future research directions and application prospects. It is expected to provide an impetus for further research and application of tartary buckwheat and provide new insights into the prevention and early treatment of obesity, hyperlipemia and diabetes.