五味子酒改善小鼠睡眠作用的研究

目的:研究探讨五味子酒对小鼠睡眠的影响。方法:将120只小鼠分为三组:纯水对照组(0.2mL/20g)、酒精对照组(0.2mL/20g)、五味子酒实验组(0.2mL/20g)。灌胃受试物10d后,进行直接睡眠实验、延长戊巴比妥钠睡眠时间实验、戊巴比妥钠阈下剂量催眠实验和巴比妥钠睡眠潜伏期实验。结果:五味子酒能够明显延长戊巴比妥钠诱导的小鼠睡眠时间,显著提高戊巴比妥钠诱导小鼠睡眠发生率,缩短巴比妥钠诱导小鼠睡眠潜伏期时间;五味子酒对小鼠无直接催眠作用,对小鼠体重无明显影响。结论:五味子酒是具有改善睡眠效果的功能性保健饮品。 

Study on the effect of schisandra wine on sleep improvement of mice

Objective:This dissertation aims to study the effect of schisandra wine on the sleep of mice.Methods:Three groups of 120 mice, the distill water group (0.2mL/20g) , alcohol group (0.2mL/20g) and the schisandra wine experiment group (0.2mL/20g) were involved in the study.After the test substances were orally given to mice for 10d, study effects of schisandra wine on induced-sleep directly of mice, and effects on duration of sleep induced by pentobarbital sodium, effects on the number of sleep induced by pentobarbital sodium under the threshold sleep dosage, and effects on the sleep latency induced by barbital sodium.Results:The result showed that the sleep time of mice was prolonged obviously, the sleeping rate of mice was increased obviously, the sleep latency was shorten obviously and there was no indirect sleep-inducing effect, and no significant effect on body weight of mice.Conclusion:Schisandra wine could improve the sleep of mice as the health food.