Subclinical multisystemic autoimmunity presenting as a progressive myelopathy |
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Authors: | G Linardaki FN Skopouli C Koufos HM Moutsopoulos |
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Affiliation: | Department of Pathophysiology, Laiko General Hospital, School of Medicine, National University of Athens, Greece. |
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Abstract: | Autoimmunity can manifest clinically in many ways; however, despite the various efforts to classify autoimmune disorders into specific disease entities, the borders between these disorders remain, in many cases, unclear. In this report we describe a young woman with subclinical Sj?gren's syndrome and biliary cirrhosis, who presents clinically with symptoms exclusively from the central nervous system. This neurological syndrome is consistent with a progressive myelopathy. Although the patient has a serologically and histologically confirmed multisystemic autoimmune disorder, she fulfills none of the classification criteria for the diagnosis of a specific connective tissue disease. |
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