Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore 560?012 (India), Fax: (+91)?80‐2360‐0683 / 2360‐1552
Abstract:
Broad‐spectrum antibiotics with heterocyclic side chains strongly inhibit peroxidase‐catalyzed iodination in the presence of metallo‐β‐lactamase. This suggests that antibiotic resistance due to hydrolysis of the β‐lactam ring in antibiotics would have negative effects on thyroid activity.