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New,Highly Active Nonbenzoquinone Geldanamycin Derivatives by Using Mutasynthesis |
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| Authors: | Simone Eichner Heinz G Floss Prof Dr Florenz Sasse Dr Andreas Kirschning Prof Dr |
| Affiliation: | 1. Zentrum für Biomolekulare Wirkstoffe (BMWZ), Leibniz Universit?t Hannover, Schneiderberg 1B, 30167 Hannover (Germany), Fax: (+49)?511‐762‐3011;2. Department of Chemistry, University of Washington, Seattle, Washington 98195‐1700 (USA);3. Abteilung Chemische Biologie, Helmholtz Zentrum für Infektionsforschung (HZI), Inhoffenstrasse 7, 38124 Braunschweig (Germany) |
| Abstract: | |
| Keywords: | antitumor agents geldanamycin Hsp90 mutasynthesis polyketides reblastatin |