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Diphenyl Ether Non‐Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties
Authors:Zachary K. Sweeney Dr.  Joshua J. Kennedy‐Smith Dr.  Jeffrey Wu  Nidhi Arora  J. Roland Billedeau  James P. Davidson Dr.  Jennifer Fretland Dr.  Julie Q. Hang Dr.  Gabrielle M. Heilek Dr.  Seth F. Harris Dr.  Donald Hirschfeld  Petra Inbar  Hassan Javanbakht Dr.  Jesper A. Jernelius Dr.  Qingwu Jin  Yu Li  Weiling Liang  Ralf Roetz  Keshab Sarma Dr.  Mark Smith Dr.  Dimitrio Stefanidis Dr.  Guoping Su Dr.  Judy M. Suh  Armando G. Villaseñor  Michael Welch  Fang‐Jie Zhang Dr.  Klaus Klumpp Dr.
Affiliation:1. Department of Medicinal Chemistry, Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304 (USA), Fax: (+1)?650‐852‐1311;2. Department of Chemical Synthesis, Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304 (USA);3. Department of Non‐Clinical Safety, Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304 (USA);4. Department of Viral Disease Biochemistry, Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304 (USA);5. Department of Viral Disease Biology, Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304 (USA);6. Department of Discovery Sciences and Technologies, Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304 (USA);7. Department of Discovery Pharmaceutics, Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304 (USA)
Abstract:
Keywords:
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