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Pharmacophore‐Based Discovery of Small‐Molecule Inhibitors of Protein–Protein Interactions between HIV‐1 Integrase and Cellular Cofactor LEDGF/p75 |
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| Authors: | Laura De?Luca Dr Maria Letizia Barreca Dr Stefania Ferro Dr Frauke Christ Dr Nunzio Iraci Dr Rosaria Gitto Prof Anna Maria Monforte Prof Zeger Debyser Prof Alba Chimirri Prof |
| Affiliation: | 1. Department of Medicinal Chemistry, University of Messina, Viale Annunziata, 98168 Messina (Italy), Fax: (+39)?090‐355613;2. Dipartimento di Chimica e Tecnologia del Farmaco, Università degli Studi di Perugia, Via del Liceo 1, 06123 Perugia (Italy), Fax: (+39)?075‐5855115;3. Molecular Virology and Gene Therapy Molecular Medicine, Katholieke Universiteit Leuven and IRC KULAK, Kapucijnenvoer 33, 3000 Leuven, Flanders (Belgium), Fax: (+32)?16‐336‐336 |
| Abstract: | |
| Keywords: | antiviral agents inhibitors HIV‐1 integrase protein– protein interactions molecular modeling |