| 2-氰乙基-5-降冰片烯-2-醛的合成 |
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| 引用本文： | 温自强,高中良,周彦峰,邱继平.2-氰乙基-5-降冰片烯-2-醛的合成[J].精细化工中间体,2007,37(5):18-19,52. |
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| 作者姓名： | 温自强 高中良 周彦峰 邱继平 |
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| 作者单位： | 河北工业大学,化工学院,天津,300310 |
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| 摘 要： | 研究了2-氰乙基-5-降冰片稀-2-醛的合成方法,其为环戊二烯-丙烯醛法生产2-氯-5-氯甲基吡啶的一个重要中间体。此中间体由丙烯腈与5-降冰片稀-2-醛经叔丁醇与氢氧化钾催化发生迈克尔加成反应而生成。通过实验得到了反应的优惠条件,目标产物的收率可达98%以上。
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| 关 键 词： | 2-氰乙基-5-降冰片稀-2-醛 迈克尔加成反应 催化剂 阻聚剂 |
| 文章编号： | 1009-9212（2007）05-0018-02 |
| 修稿时间： | 2007-09-15 |
Synthesis of 2-Cyanoethyl-5-norbornene-2-carboxaldehyde |
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| WEN Zi-qiang,GAO Zhong-liang,ZHOU Yan-feng,QIU Ji-ping.Synthesis of 2-Cyanoethyl-5-norbornene-2-carboxaldehyde[J].Fine Chemical Intermediates,2007,37(5):18-19,52. |
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| Authors: | WEN Zi-qiang GAO Zhong-liang ZHOU Yan-feng QIU Ji-ping |
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| Affiliation: | College of Chemical Engineering, Hebei University of Technology, Tianjin 300130, China |
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| Abstract: | The compound 2-cyanoethyl-5-norbornene-2-carboxaldehyde is a key intermediate of 2-chloro-5-chloromethylpyridine through cyclopentadiene-acraldehyde method. 2-cyanoethyl-5-norbornene-2-carboxaldehyde was synthesized through a Michael addition reaction of acrylonitrile and 5-norbornene-2-carboxaldehyde using tert-butyl alcohol and potassium hydroxide as catalyst at room temperature. The optimum reaction conditions were obtained via experiments with a yield of the title product of above 98%. |
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| Keywords: | 2-cyanoethyl-5-norbornene-2-carboxaldehyde Michael addition reaction catalyst retarder |
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