| lipstatin发酵工艺的优化 |
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| 引用本文： | 颜震,李海军,朱希强,李志民,赵国敏,郭学平,凌沛学. lipstatin发酵工艺的优化[J]. 食品与药品, 2007, 9(12): 5-7 |
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| 作者姓名： | 颜震 李海军 朱希强 李志民 赵国敏 郭学平 凌沛学 |
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| 作者单位： | 山东省药学科学院,国家糖工程研究中心,山东,济南,250108 |
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| 摘 要： | 目的优化lipstatin的发酵工艺。方法采用摇瓶发酵,改变实验条件,通过测定lipstatin含量来确定较为适合的发酵工艺。结果优化后的培养基组成为:豆油8.0%,甘油0.7%,黄豆粉3.0%,酵母粉1.0%,TritonX-100 0.1%。在此条件下lipstatin发酵产量为156.8 mg/L。结论提高了lipstatin产量。
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| 关 键 词： | lipstatin 毒三素链霉菌 发酵工艺 |
| 文章编号： | 1672-979X(2007)12-0005-03 |
| 修稿时间： | 2007-10-20 |
Fermentation Process Optimization of Lipstatin |
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| YAN Zhen,LI Hai-jun,ZHU Xi-qiang,LI Zhi-min,ZHAO Guo-min,GUO Xue-ping,LING Pei-xue. Fermentation Process Optimization of Lipstatin[J]. Food and Drug, 2007, 9(12): 5-7 |
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| Authors: | YAN Zhen LI Hai-jun ZHU Xi-qiang LI Zhi-min ZHAO Guo-min GUO Xue-ping LING Pei-xue |
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| Abstract: | Objective To optimize the fermentation process of lipstatin.Methods In shaken flask culture,the yieldof lipstatin was determined under the different experiment conditions in order to obtain an optimal fermentation process.Results The optimal medium contained 8.0 % bean oil,0.7 % glycerol,3.0 % soybean powder,1.0 % yeast extractpowder,0.1 % TritonX-100.The yield of lipstatin was 156.8 mg/L.Conclusion The yield of lipstatin can be improved. |
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| Keywords: | lipstatin Streptomyces toxytricini fermentation process |
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