Abstract: | Total and nonsedimentable cathepsin A, B, C and D activity was studied in the liver and kidneys, as well as in the blood serum of rats fed with rations containing protein isolate from krill (100 and 50%) and krill flesh (100%) during .6 and 12 months. Selective activation of cathepsins A dn D in the liver, intensified nonsedimentable activity of all lysosomal proteinases studied, most manifest at the initial stages of the experiment (4 months), and a sharp (0.5-3.5-fold) rise of these enzymes' activity in the blood serum were recorded in rats when the krill isolate served the only source of protein (100%) in their ration. |