New calcium‐free Na2O–Al2O3–P2O5 bioactive glasses with potential applications in bone tissue engineering |
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| Authors: | Oliwia Jeznach Marcin Gajc Karolina Korzeb Andrzej K?os Krzysztof Orliński Ryszard St?pień Ma?gorzata Krok‐Borkowicz ?ucja Rumian Krzysztof Pietryga Katarzyna Reczyńska El?bieta Pamu?a Dorota A Pawlak |
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| Affiliation: | 1. Institute of Electronic Materials Technology, Warsaw, Poland;2. Department of Biomaterials, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Krakow, Poland;3. Centre of New Technologies, Warsaw, Poland |
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| Abstract: | Sodium aluminophosphate glasses were evaluated for their bone repair ability. The glasses belonging to the system 45Na2O–xAl2O3‐(55‐x)P2O5, with x = (3, 5, 7, 10 mol%) were prepared by a melt‐quenching method. We assessed the effect of Al2O3 content on the properties of Na2O–Al2O3–P2O5 (NAP) glasses, which were characterized by density measurements, DSC analyses, solubility, bioactivity in simulated body fluid and cytocompatibility with MG‐63 cells. To the best of our knowledge, this is the first investigation of calcium‐free Na2O–Al2O3–P2O5 system glasses as bioactive materials for bone tissue engineering. |
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| Keywords: | alumina bioactive glass bone tissue engineering calcium‐free bioactive glass phosphate glass sodium aluminophosphate glass |
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