| 丹参提取液体外抑菌活性研究 |
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| 引用本文： | 王庆银,姚庆强.丹参提取液体外抑菌活性研究[J].食品与药品,2010,12(5):184-187. |
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| 作者姓名： | 王庆银 姚庆强 |
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| 作者单位： | 王庆银(山东省医学科学院药物研究所,山东,济南,250062;济宁市药品检验所,山东,济宁,272025);姚庆强(山东省医学科学院药物研究所,山东,济南,250062) |
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| 摘 要： | 目的 研究丹参提取液的体外抑菌作用.方法 采用常量肉汤稀释法测定最低抑菌浓度(MIC),探讨其体外抑菌作用.采用杯碟法检测丹参不同提取方式、不同灭菌方式以及改变提取液pH值对金黄色葡萄球菌抑菌活性的影响.结果 丹参醇提液对大肠埃希菌、金黄色葡萄球菌、枯草芽胞杆菌、铜绿假单胞杆菌、短小芽胞杆菌均有抑菌作用,其95%醇提液对上述菌的MIC分别为20,20,40,80,80 mg/mL,对白色念珠菌无抑菌作用.丹参醇提液对大肠埃希菌、金黄色葡萄球菌抑菌活性较强;不同灭菌方式及改变提取液pH值对金黄色葡萄球菌抑菌活性无差异.结论 丹参提取液具有一定抑菌作用.
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| 关 键 词： | 丹参 最低抑菌浓度 抑菌作用 |
Study on Antimicrobial Activity in Vitro of Extract from Salviae miltiorrhizae Radix et Rhizoma |
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| WANG Qing-yin,YAO Qing-qiang.Study on Antimicrobial Activity in Vitro of Extract from Salviae miltiorrhizae Radix et Rhizoma[J].Food and Drug,2010,12(5):184-187. |
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| Authors: | WANG Qing-yin YAO Qing-qiang |
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| Affiliation: | WANG Qing-yin1,2,YAO Qing-qiang1(1.Institute of Materia Medica,Shandong Academy of Medical Sciences,Jinan 250062,China,2.Jining Institute for Drug Control,Jining 272025,China) |
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| Abstract: | Objective To study the antimicrobial activity in vitro of the extract from Salviae miltiorrhizae Ratix et Rhizoma.Methods The minimum inhibitory concentration(MIC) of the extract was determined by the constant broth dilution method,in order to investigate the antimicrobial activity in vitro.The activities of extracts extracted with different extraction methods,different sterilization methods,or at different pH against Staphylococcus aureus were determined by the cylinder-plate method.Results The ethanolic e... |
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| Keywords: | Salviae miltiorrhizae Radix et Rhizoma minimum inhibitory concentration antimicrobial activity |
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