Baseline glomerular size as a predictor of function in human renal transplantation

PURPOSE: To determine whether non-central retinal vein occlusion (nCRVO) or open angle glaucoma (OAG) is the primary event in eyes suffering from both diseases. METHODS: The study has two parts. The first is a retrospective survey of a clinical glaucoma database. In eyes with OAG and nCRVO, the temporal relationship between the conditions was determined when possible. The second part is a ten-year follow-up study of eyes with isolated nCRVO. RESULTS: Study 1: Among 576 OAG patients, 25 (4.3%) had nCRVO. In all eyes except one, OAG occurred before nCRVO. Almost without exception a vein on the optic disk or at the disk margin was occluded. Study 2: Most eyes with isolated nCRVO had an occluded vein at a retinal artery-vein crossing. Only one of 34 patients had developed OAG after ten years. CONCLUSIONS: This study suggests that OAG in most eyes is the primary event. nCRVO had different characteristics in eyes with OAG compared to eyes without OAG.