Hypolipidemic study of xylanase-modified corn bran fibre in rats |
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| Authors: | Ye-Bi Hu Xiang-Jin Fu Feng-Xiang Zhang Fu-Min Ma Zhang Wang Shi-Ying Xu |
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| Affiliation: | 1. School of Food Science and Engineering, Central South University of Forestry and Technology, No. 498 Shaoshan Road, Changsha 410000, PR China;2. State Key Laboratory of Food Science and Technology, Jiangnan University, Box 98, No.1800 Lihu Road, Wuxi 214036, PR China |
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| Abstract: | In order to understand the regulatory effect of xylanase-modified corn bran fibre (XMF) on lipid homeostasis, detailed influences, following the ingestion of XMF and its original form (corn bran dietary fibre, CDF), on serum, liver and faecal lipids were studied in Sprague–Dawley rats. In both CDF and XMF groups, serum total cholesterol (TC), triacylglycerol (TG) and low-density lipoprotein cholesterol (LDL-C) were significantly lowered after 4 weeks (p < 0.05). By the end of week 6, data in the XMF group showed that serum LDL-C was lowered further and high-density lipoprotein cholesterol (HDL-C) was significantly increased (p < 0.05); liver TC, TG and fat were significantly lower (p < 0.05), while the excretions of faecal fat, TC and bile acids were significantly higher (p < 0.05). The decrease of liver and serum lipids in the XMF group was consistent with the improved excretion of faecal lipids and bile acids. Other related mechanisms are also considered. |
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| Keywords: | Xylanase modification Corn bran fibre Serum lipids Liver lipids Lipids excretion Hypolipidemic study |
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