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Quali-quantitative analysis of flavonoids of Cornus mas L. (Cornaceae) fruits
Authors:Agata Maria Pawlowska  Fabiano Camangi  Alessandra Braca
Affiliation:1. Dipartimento di Scienze Farmaceutiche, Università di Pisa, Via Bonanno 33, 56126 Pisa, Italy;2. Scuola Superiore S. Anna di Studi, Universitari e di Perfezionamento di Pisa, Piazza Martiri della, Libertà 33, 56127 Pisa, Italy
Abstract:The methanol extract obtained from the ripe fruits of Cornus mas L. (Cornaceae) have been phytochemically studied. On the basis of HPLC–PDA–MS/MSn analysis eight compounds have been identified as quercetin, kaempferol, and aromadendrin glycosilated derivatives. Three major compounds have been also isolated by Sephadex LH-20 column chromatography followed by HPLC and characterised by NMR spectroscopy. Moreover, LC–PDA–MS analysis of the red pigment revealed the presence of three anthocyanins. The quantitative analysis of all compounds was reported.
Keywords:Cornus mas  Flavonoids  Anthocyanins  HPLC  ESI-MS/MS
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