酸浆中木犀草苷提取工艺优化

目的 优化酸浆中木犀草苷成分的提取工艺.方法 选取干燥的酸浆[Physalisalkekengi L.var.franchetii(Mast.)Makino]宿萼作为实验材料,分别使用甲醇、乙醇和水作为溶剂,考察超声、热回流和渗漉对木犀草苷提取效率的影响.结果 以乙醇作为提取溶剂,采用加热回流的提取方式,木犀草苷得率较...

Optimization of extraction process of luteoloside from Physalis alkekengi L. var. franchetii (Mast.) Makino

Objective A high-efficient, simple, convenient and safe method for extraction of luteolin from Physalisalkekengi L.var. franchetii (Mast.) Makino was developed and optimized by single-factor experiment and orthogonal experiment. Methods For extraction of luteoloside from the dried calyxes of Physalisalkekengi L.var. franchetii (Mast.) Makino, the solvents of methanol, ethanol and water, and the methods of ultrasonic, heating reflux extraction and percolation were investigated, respectively. Results The results showed that the yield of luteoloside was higher by using the solvent of ethanol and the method of heating reflux. Then, single factor experiment and orthogonal experiment were applied for further optimization of the extraction process. The results showed that the yield of luteoloside was increased to 1.28% by using the solvent of 95% ethanol, the ratio of material to solvent 1:30 (g/mL), heating reflux extraction for 90 min, extraction of 3 times. Conclusion After optimization of the processes, the extraction rate of luteoloside was significantly improved.