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Cover Feature: A DNA‐Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition (ChemMedChem 13/2018)
Authors:Nicholas Favalli  Stefan Biendl  Marco Hartmann  Dr. Jacopo Piazzi  Dr. Filippo Sladojevich  Dr. Susanne Gräslund  Dr. Peter J. Brown  Dr. Katja Näreoja  Prof. Dr. Herwig Schüler  Dr. Jörg Scheuermann  Prof. Dr. Raphael Franzini  Prof. Dr. Dario Neri
Affiliation:1. Institute of Pharmaceutical Sciences, ETH Zürich, Zürich, Switzerland;2. Philochem AG, Otelfingen, Switzerland;3. Roche Pharma Research and Early Development, Roche Innovation Center Basel, F.?Hoffmann-La, Roche Ltd., Basel, Switzerland;4. Structural Genomics Consortium (SGC), University of Toronto, Toronto, ON, Canada;5. Department of Structural Biology, Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet, Stockholm, Sweden;6. College of Pharmacy, University of Utah, Salt Lake City, UT, USA
Abstract:
Keywords:bifunctional ligands  DNA-encoded chemical libraries  human serum albumin  tankyrase-1
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